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Physiological and morphological peculiarities of children with Down’s syndrome: A brief review


Background: There are several approaches to solve the problems of many pathological processes’ correction, such as clinical pathology and experiment in modern science. At the same time, genetically-conditioned diseases usually demand researchers’ attention and generalization of earlier information for making the correction foundation of their manifestations in the future. Down’s syndrome is considered to be one. Our objective was to review existing literature regarding physiological and morphological peculiarities of children with Down’s syndrome.

Methods: A total of 30 relevant literature were reviewed regarding physiological and morphological peculiarities of children with Down’s syndrome. The data collection for eligible articles were conducted from 1989-2017. Different database and manual search methods were used to find the topic-related articles.

Results: Abnormalities of heart, gastrointestinal tract and the system of urinary excretion are considered as the underlying congenital abnormalities for children with Down’s syndrome influencing their lifespan. People with Down’s syndrome have difficulties in their cognitive activity, such as lag in development, speaking, and reading. Limitation existence of ideas and scarcity of conclusions make studying different school subjects impossible for children with Down’s syndrome. They need more time to master new skills and remembering new material. On the other hand, children with Down’s syndrome possess positive personal qualities: they are tender, friendly and even-tempered. Conclusion: Down’s syndrome is considered as one of the most common genetic diseases occurred newborns. Children with Down’s syndrome have several physical abnormalities. It is important to understand children with Down’s syndrome as a whole, as they can be put into a well-adjusted system of rehabilitation.


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How to Cite

Makhov, A., & Medvedev, I. N. (2020). Physiological and morphological peculiarities of children with Down’s syndrome: A brief review. Bali Medical Journal, 9(1), 51–54.




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A.S. Makhov
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Ilya Nikolayevich Medvedev
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