Management of von willebrand disease in pregnancy in resource-limited settings: a case report

I Wayan Losen Adnyana

I Wayan Losen Adnyana
Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Udayana, Bali Indonesia. Email:
Online First: October 30, 2020 | Cite this Article
Adnyana, I. 2020. Management of von willebrand disease in pregnancy in resource-limited settings: a case report. Bali Medical Journal 9(3): 702-704. DOI:10.15562/bmj.v9i3.2044

Background: Von Willebrand's disease (VWD) is the most common autosomal dominant bleeding disorder. Pregnancy and delivery in patient with VWD possess significant clinical challenges.

Case description: a 24-year-old woman who will undergo labor with a history of VWD.  The patient was planned for induction of vaginal delivery and has been given intranasal desmopressin, cryoprecipitate, and factor VIII from before delivery to 5 days after delivery. Labor occurs without excess bleeding. The patient was monitored for 6 days after delivery, and there is no complication of excessive bleeding.

Conclusion: This case emphasizes how to manage Von Willebrand's disease in pregnancy with limitation in the examination and therapeutic option, also the importance of joint management from the hematologist, obstetrician, starting from the antepartum, delivery, and postpartum phases.


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