ORIGINAL ARTICLE

Relationship of gallbladder histopathology towards types of stones in cholelithiasis patients at Universitas Sumatera Utara Hospital, Medan, Indonesia

Adi Muradi Muhar , Denny Rifsal Siregar, Doddy Prabisma

Adi Muradi Muhar
Digestive Surgery Division, Surgery Department, Faculty of Medicine, Universitas Sumatera Utara-Haji Adam Malik Hospital, Medan, Indonesia. Email: adibedah@gmail.com

Denny Rifsal Siregar
Surgery Department, Faculty of Medicine, Universitas Sumatera Utara-Haji Adam Malik General Hospital, Medan Indonesia

Doddy Prabisma
Surgery Department, Faculty of Medicine, Universitas Sumatera Utara-Haji Adam Malik General Hospital, Medan Indonesia
Online First: January 25, 2021 | Cite this Article
Muhar, A., Siregar, D., Prabisma, D. 2021. Relationship of gallbladder histopathology towards types of stones in cholelithiasis patients at Universitas Sumatera Utara Hospital, Medan, Indonesia. Bali Medical Journal 10(1): 1-3. DOI:10.15562/bmj.v10i1.2128


Background: Cholelithiasis is a common disease of the gall bladder. It is estimated that around 10-15% of the population in western countries suffer from cholelithiasis. Types of gall bladder stones can be classified into cholesterol stones (containing cholesterol> 50%), mixed stones (containing 20-50% cholesterol), and pigment stones (containing cholesterol <20%). Cholelithiasis causes various histopathological changes in the gallbladder mucosa such as acute and chronic inflammation, Cholelithiasis, hyperplasia and carcinoma. The general objective of this study was to determine the histopathological relationship of the gallbladder to the type of stone in cholelithiasis patients at USU Hospital.

Method: The design in this study was cross-sectional. The sample of this study was 49 samples of patients with cholelithiasis who underwent cholecystectomy either by open cholecystectomy or per-laparoscopic cholecystectomy at Universitas Sumatera Utara (USU) Hospital. Gallstones and gall bladder will be examined in the laboratory. Data analysis will use the chi-square test.

 

Result: From 49 research samples found the most types of stones were mixed stones with 24 (49%) and histopathological results showed 18 examples (36.7%) were chronic inflammation. Based on the Chi-Square test found a significant relationship between the types of stones with histopathology of the gallbladder with a p-value of 0.001.

 

Conclusion: There is a significant relationship between the type of stone with histopathology in patients with cholelithiasis.

 

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