ORIGINAL ARTICLE

Amino acid methionine, lysine and vitamin choline: A potential feed supplement to reduce mortality, improve immunity, and health of Bali pigs in the growth phase

Ida Bagus Komang Ardana , Ketut Sumadi, Ketut Budiasa, Anak Agung Gde Oka Dhamayudha, Hamong Suhasono, Nico Fajar Gunawan

Ida Bagus Komang Ardana
Veterinary Pathology Clinic, Faculty of Veterinary Medicine, Universitas Udayana, Bali, Indonesia. Email: ardana.idabagus@gmail.com

Ketut Sumadi
Laboratory of Animal Feeding, Faculty of Veterinary Medicine, Universitas Udayana, Bali, Indonesia

Ketut Budiasa
Laboratory of Pharmacology Veterinary, Faculty of Veterinary Medicine, Universitas Udayana, Bali, Indonesia

Anak Agung Gde Oka Dhamayudha
Laboratory of Surgery and Radiology, Faculty of Veterinary Medicine, Universitas Udayana, Bali, Indonesia

Hamong Suhasono
Laboratory of Biochemistry, Faculty of Veterinary Medicine, Universitas Udayana, Bali, Indonesia

Nico Fajar Gunawan
Laboratory of Radiology, Faculty of Veterinary Medicine, Universitas Udayana, Bali, Indonesia
Online First: August 21, 2021 | Cite this Article
Ardana, I., Sumadi, K., Budiasa, K., Dhamayudha, A., Suhasono, H., Gunawan, N. 2021. Amino acid methionine, lysine and vitamin choline: A potential feed supplement to reduce mortality, improve immunity, and health of Bali pigs in the growth phase. Bali Medical Journal 10(2): 753-756. DOI:10.15562/bmj.v10i2.2363


Introduction: Balinese piglets, separated from the mother and given traditional feeding, can cause prolonged growth. So, it is necessary to provide feed with a complete formula to support the growth process. Previous studies reported that Balinese piglets fed with a mixture of yellow corn, pollard, Aminovite, table salt, and minerals with several formulations and a metabolized energy (ME)/crude protein (CP) ratio 2800 kcal/kg/12% significantly increased body weight. However, his health status has not been reported, both the hematological profile and antibody titer. The purpose of this study was to determine the effect of the amino acid methionine, lysine, and choline (Aminovite) on health, hematological profile, and antibody titer as immunomodulatory effects.

Methods: This study used 72 Balinese piglets after being separated from the mother, divided into four groups of 18 piglets each. The first group (P0) was given basic feed mixtures of corn and pollard as a control. The second group (P1) was fed P0 + 0.5% Aminovite. The third group (P2) was fed P0 + 1.00% Aminovite. The fourth group (P3) was fed P0 + 1.50% Aminovite. Bali piglets are vaccinated with the Hog Cholera vaccine. Furthermore, on the 12th day of the week after treatment (aged 80-90 days), a hematological profile examination will be carried out, and the antibody titer of Hog Cholera will be examined. The data were analyzed using the One Way Anova test and Duncan's Multiple Range Test. The p-value <0.05 is significant.

Result: There was no mortality of piglets in all groups, but the control group had a high morbidity rate (22.2%) than the other groups. Aminovite mixed in the feed significantly increased WBC, total RBC, Hb levels, and PCV values compared to control (p<0.05). Aminovite can also increase neutrophils and monocytes and significantly reduce lymphocytes compared to control (p<0.05).

Conclusion: The addition of Aminovite as a feed supplement in Balinese piglet feed improved the health of Bali piglets seen from the blood profile and increased Antibody titers resulting from Hog Cholera vaccination. 

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