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The difference of platelet-white blood cell ratio in severe preeclampsia and normotensive pregnancy

Abstract

Background: Inflammation is believed to play a role in preeclampsia. Leukocytes increase due to inflammatory response. Endothelial damage in preeclampsia induces platelet aggregation, triggers platelet consumption, and decreases platelet. Therefore, preeclampsia could alter the platelet-white blood cell ratio, which can be used as a marker for preeclampsia. This study examines the difference of platelet-white blood cell ratio in severe preeclampsia and normotensive pregnancy.

Methods: This study used the medical records of pregnant women in Dr. Kariadi General Hospital Semarang from 2019 to 2020. Samples were collected using a consecutive sampling method. Data were analyzed using an independent t-test and Mann-Whitney.

Results: There was a significant difference in platelet count (p=0.011) and leukocyte count (p=0.018) between severe preeclampsia and normotensive pregnancy. Therefore, a difference (p<0.01) in platelet-white blood cell ratio between severe preeclampsia and normotensive pregnancy was observed.

Conclusion: Platelet-white blood cell ratio in severe preeclampsia is 0.7 times lower than in normotensive pregnancy.

References

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How to Cite

Nur Safirani, N. A., Fulyani, F., Wiyati, P. S., & Pramono, B. A. (2022). The difference of platelet-white blood cell ratio in severe preeclampsia and normotensive pregnancy. Bali Medical Journal, 11(1), 414–417. https://doi.org/10.15562/bmj.v11i1.3246

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Nisrina Aisyah Nur Safirani
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Faizah Fulyani
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Putri Sekar Wiyati
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Besari Adi Pramono
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