Skip to main content Skip to main navigation menu Skip to site footer

The effect of boxing exergame on blood lactate and VO2max in non-athlete healthy young men


Background: The lack of physical activity and high sedentary behavior is among the main causes of non-communicable diseases at a young age. Moreover, exergaming (EXG) is a type of exercise that integrates different modes of digital games into physical activities. Since several young men spend a significant amount of time on sedentary games, it is believed that replacement with exergames will improve physical activity levels. Therefore, this study was carried out to evaluate the effectiveness of exercise by measuring blood lactate (BLa) and VO2max in non-athlete healthy young men. This study aims to analyze the effect of exercise using NintendoTM switch "Fitness Boxing 2" on BLa and VO2max in non-athlete healthy young men.

Methods: Experimental series with repeated measures on healthy young men of 20-40 years by the health worker at Dr. Soetomo Hospital Surabaya. This research was based on the exercise using Nintendo SwitchTM "Fitness Boxing 2" with the hard or high-intensity mode at a duration of 38 minutes consisting of warm-up, core training which included variations of Straight, Hook, and Uppercut strokes, and cooling down three times a week for one month. The BLa examination was carried out 3 times before and after exercises I, VI, and XII during the exercise. VO2max was examined using the 6-minutes walking test based on the Nusdwinuringtyas formula one day before and after exercises I and XII, respectively.

Results: This study included 13 healthy young men, with an average age of 30.77± 3.632. The mean BLa before and after exercise was 2.03 and 3.02, respectively, with an increase of 0.99. The three p-values ​​were carried out by the Wilcoxon Signed Rank Test, where a p-value = 0.001 was obtained, indicating a significant increase in post-exercise BLa levels. The VO2max before and after treatment obtained an average of 23.39± 2.82 (mL/kg/minute) and 30.69 ± 4.95 (mL/kg/minute), respectively. Furthermore, the comparison of VO2max examination before and after treatment with an average of 7.30±4.04 (mL/kg/min) obtained a significant difference with a p-value = 0.000.

Conclusion: The effect of high-intensity exercise using Nintendo SwitchTM "Fitness Boxing 2" increases the BLa levels and VO2max in non-athlete healthy young men.


  1. World Health Organization. The global burden of disease: 2004 update. World Health Organization; 2008.
  2. Finkelstein EA, Ruhm CJ, Kosa KM. Economic causes and consequences of obesity. Annu Rev Public Health. 2005;26(1):239–57. Available from:
  3. Ludwig DS, Pollack HA. Obesity and the Economy. JAMA. 2009;301(5):533. Available from:
  4. Amiri M. Sedentary behavior in young people and related complications: An international challenge [Internet]. 2018. Available from: 10.1161/CIR.0000000000000591
  5. Bonetti AJ, Drury DG, Danoff J V, Miller TA. Comparison of Acute Exercise Responses Between Conventional Video Gaming and Isometric Resistance Exergaming. J Strength Cond Res. 2010;24(7):1799–803. Available from:
  6. Sato T, Shimizu K, Shiko Y, Kawasaki Y, Orita S, Inage K, et al. Effects of Nintendo Ring Fit Adventure Exergame on Pain and Psychological Factors in Patients with Chronic Low Back Pain. Games Health J. 2021;10(3):158–64. Available from:
  7. Meekes W, Stanmore EK. Motivational Determinants of Exergame Participation for Older People in Assisted Living Facilities: Mixed-Methods Study. J Med Internet Res. 2017;19(7):e238–e238. Available from:
  8. Gerling KM, Schild J, Masuch M. Exergame design for elderly users [Internet]. Proceedings of the 7th International Conference on Advances in Computer Entertainment Technology - ACE ’10. ACM Press; 2010. Available from:
  9. Naugle KE, Naugle KM, Wikstrom EA. Cardiovascular and affective outcomes of active gaming: using the nintendo wii as a cardiovascular training tool. J strength Cond Res. 2014;28(2):443–51. Available from:
  10. Lange B, Flynn S, Proffitt R, Chang C-Y, “Skip” Rizzo A. Development of an Interactive Game-Based Rehabilitation Tool for Dynamic Balance Training. Top Stroke Rehabil. 2010;17(5):345–52. Available from:
  11. Dempsey P. The Teardown: Nintendo Switch gaming system. Eng & Technol. 2017;12(4):82–3. Available from:
  12. Nintendo. Fitness Boxing for Nintendo Switch - Nintendo Official Site [Internet]. 2019. Available from:
  13. Riebe D, Ehrman JK, Liguori G, Magal M, Medicine AC of S. ACSM’s guidelines for exercise testing and prescription. Wolters Kluwer; 2018.
  14. American Thoracic Society. Erratum: ATS Statement: Guidelines for the Six-Minute Walk Test. Am J Respir Crit Care Med. 2016;193(10):1185. Available from:
  15. Nusdwinuringtyas N, Widjajalaksmi W, Bachtiar A. Healthy adults maximum oxygen uptake prediction from a six minute walking test. Med J Indones. 2011;195. Available from:
  16. Valenzuela T, Okubo Y, Woodbury A, Lord SR, Delbaere K. Adherence to Technology-Based Exercise Programs in Older Adults: A Systematic Review. J Geriatr Phys Ther. 2018;41(1):49–61. Available from:
  17. Goodwin ML, Harris JE, Hernández A, Gladden LB. Blood lactate measurements and analysis during exercise: a guide for clinicians. J Diabetes Sci Technol. 2007;1(4):558–69. Available from:
  18. BROOKS GA. Anaerobic threshold. Med & Sci Sport & Exerc. 1985;17(1):22???31. Available from:
  19. Wasserman K, Whipp BJ, Koyl SN, Beaver WL. Anaerobic threshold and respiratory gas exchange during exercise. J Appl Physiol. 1973;35(2):236–43. Available from:
  20. Mader AH. Zur beurteilung der sportartspezifischen ausdauerleistungsfahigkeit im labor. Sport Sport. 1976;27:80–8.
  21. Kindermann W, Simon G, Keul J. The significance of the aerobic-anaerobic transition for the determination of work load intensities during endurance training. Eur J Appl Physiol Occup Physiol. 1979;42(1):25–34. Available from:
  22. Skinner JS, Mclellan TH. The Transition from Aerobic to Anaerobic Metabolism. Res Q Exerc Sport. 1980;51(1):234–48. Available from:
  23. Karlsson J, Holmgren A, Linnarson D, Åström H. OBLA Exercise Stress Testing in Health and Disease [Internet]. Progress in Ergometry: Quality Control and Test Criteria. Springer Berlin Heidelberg; 1984. p. 67–91. Available from:
  24. Jöbsis FF, Stainsby WN. Oxidation of NADH during contractions of circulated mammalian skeletal muscle. Respir Physiol. 1968;4(3):292–300. Available from:
  25. Green HJ, Hughson RL, Orr GW, Ranney DA. Anaerobic threshold, blood lactate, and muscle metabolites in progressive exercise. J Appl Physiol. 1983;54(4):1032–8. Available from:
  26. Connett RJ, Gayeski TE, Honig CR. Lactate accumulation in fully aerobic, working, dog gracilis muscle. Am J Physiol Circ Physiol. 1984;246(1):H120–8. Available from:
  27. Millan IS. What is Lactate and Lactate Threshold. [Internet]. Training Article. 2014. Available from:
  28. Storniolo JL, Pavei G, Minetti AE. A “Wearable” Test for Maximum Aerobic Power: Real-Time Analysis of a 60-m Sprint Performance and Heart Rate Off-Kinetics. Front Physiol. 2017;8:868. Available from:
  29. Howley ET, Thompson DL. Fitness professional’s handbook. Human Kinetics; 2022.
  30. Jang WY, Kim W, Kang DO, Park Y, Lee J, Choi JY, et al. Reference Values for Cardiorespiratory Fitness in Healthy Koreans. J Clin Med. 2019;8(12):2191. Available from:
  31. Huang G, Wang R, Chen P, Huang SC, Donnelly JE, Mehlferber JP. Dose–response relationship of cardiorespiratory fitness adaptation to controlled endurance training in sedentary older adults. Eur J Prev Cardiol. 2015;23(5):518–29. Available from:
  32. Rebsamen S, Knols RH, Pfister PB, de Bruin ED. Exergame-Driven High-Intensity Interval Training in Untrained Community Dwelling Older Adults: A Formative One Group Quasi- Experimental Feasibility Trial. Front Physiol. 2019;10:1019. Available from:
  33. Berg J, Haugen G, Wang AI, Moholdt T. High-intensity exergaming for improved cardiorespiratory fitness: A randomised, controlled trial. Eur J Sport Sci. 2021;22(6):867–76. Available from:

How to Cite

Fairuz Silvi, Raden Ayu Meisy Andriana, Indrayuni Lukitra Wardhani, Yudith Dian Prawitri, Inggar Narasinta, & Soenarnatalina Melaniani. (2022). The effect of boxing exergame on blood lactate and VO2max in non-athlete healthy young men . Bali Medical Journal, 11(2), 827–831.




Search Panel

Fairuz Silvi
Google Scholar
BMJ Journal

Raden Ayu Meisy Andriana
Google Scholar
BMJ Journal

Indrayuni Lukitra Wardhani
Google Scholar
BMJ Journal

Yudith Dian Prawitri
Google Scholar
BMJ Journal

Inggar Narasinta
Google Scholar
BMJ Journal

Soenarnatalina Melaniani
Google Scholar
BMJ Journal