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Evaluation of the accordance of dermoscopy and histopathological examination results in patients who were clinically diagnosed as basal cell carcinoma

  • Berliana Kurniawati Nur Huda ,
  • Muhammad Yulianto Listiawan ,
  • Dwi Murtiastutik ,
  • Budi Utomo ,
  • Bagus Haryo Kusumaputra ,
  • Maylita Sari ,
  • Irmadita Citrashanty ,

Abstract

Introduction: The incidence of basal cell carcinoma (BCC) has increased in recent decades, especially in people of color. Early diagnosis is needed as a preventive measure. The use of dermoscopy increases the sensitivity of diagnosis when combined with clinical examination using the naked eye. Histopathological examination is used as the gold standard examination to confirm the diagnosis. This retrospective study was conducted to evaluate the suitability of the results of dermoscopic and histopathological examinations in patients clinically diagnosed as BCC, to increase knowledge, help to train approaches to BCC diagnosis and serve as a consideration in making decisions on histopathological examination and further management for patients with BCC.

Method: A cross-sectional retrospective study design with an analytic observational study. A total sampling technique was performed from the patient’s medical records with a diagnosis of BCC. Analysis of the concordance of the results of dermoscopic and histopathological examinations in patients clinically diagnosed as BCC was analyzed using Fisher's exact test.

Result: There were 29 subjects in total. Dermoscopically, 23 subjects and 6 subjects were diagnosed as BCC and non-BCC. Histopathologically, 20 subjects and 9 subjects were confirmed as BCC and non-BCC. The concordance of dermoscopy and histopathological diagnosis showed k = 0.56 with 95% sensitivity, 55.6% specificity, 82.76% accuracy, 2.14 positive likelihood ratio (LR+), and 0.09 negative likelihood ratio (LR-). Dermoscopic features with shiny white areas were the most dominant feature (RR= 8,167).

Conclusion: Dermoscopy and histopathology have a significant concordance in diagnosing BCC. Dermoscopy can sharpen clinical examination in diagnosing BCC. The appearance of shiny white structures can increase our awareness of the diagnosis of BCC through dermoscopy, especially in people of color.

References

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How to Cite

Huda, B. K. N., Listiawan, M. Y. ., Murtiastutik, D. ., Utomo, B. ., Kusumaputra, B. H. ., Sari, M. ., & Citrashanty, I. . (2024). Evaluation of the accordance of dermoscopy and histopathological examination results in patients who were clinically diagnosed as basal cell carcinoma. Bali Medical Journal, 13(2), 519–523. https://doi.org/10.15562/bmj.v13i2.5131

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Berliana Kurniawati Nur Huda
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Muhammad Yulianto Listiawan
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Dwi Murtiastutik
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Budi Utomo
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Bagus Haryo Kusumaputra
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Maylita Sari
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Irmadita Citrashanty
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