Myocardial pathological changes in overtraining exercise

Made Kurnia Widiastuti Giri , Ketut Indra Purnomo, Muchsin Doewes, Bambang Purwanto, Ambar Mudigdo

Made Kurnia Widiastuti Giri
Lecturer, Faculty of Sports and Health Sciences, Universitas Pendidikan Ganesha, Singaraja, Bali, Indonesia. Email: drnia82@gmail.com

Ketut Indra Purnomo
Lecturer, Faculty of Sports and Health Sciences, Universitas Pendidikan Ganesha, Singaraja, Bali, Indonesia

Muchsin Doewes
Lecturer, Department of Medical Sciences, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia

Bambang Purwanto
Lecturer, Department of Medical Sciences, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia

Ambar Mudigdo
Clinical Pathology Specialist and Lecturer, Department of Medical Sciences, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia
Online First: July 18, 2017 | Cite this Article
Giri, M., Purnomo, K., Doewes, M., Purwanto, B., Mudigdo, A. 2017. Myocardial pathological changes in overtraining exercise. Bali Medical Journal 6(3): 505-508. DOI:10.15562/bmj.v6i3.547

Background: An overtraining or a practice of an excessive intensity without a sufficient recovery period may induce myocardial injury. Objective: The aim of this study was to reveal myocardial changes in overtrained rats through a histo-pathobiological analysis. Methods: We enrolled 24 male Wistar rats for 6 weeks. As many as 8 rats or the control group swam 15 minute/day, 5 days/week. The overtrained group consisted of 24 rats swam for 90 minutes, twice a day, daily. After sacrificing, the hearts were excised for pathological preparation slides. Results: The overtrained group’s slides showed an increase in chromatin fragmentation in the myocardial structure. The left ventricle wall thickness was also greater in overtrained groups than the control. Necrotic bodies were found in the myocardium of overtrained groups, but none in the control group. Conclusion: We found the negative effects of an overtraining to the myocardium. Avoiding overtraining is necessary to avoid a myocardial injury.


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