Skip to main content Skip to main navigation menu Skip to site footer

Greater carotid intima-media thickness in elderly patients compare to the non-elderly regular hemodialysis patients

  • Ketut Gede Wiradharma ,
  • R. A. Tuty Kuswardhani ,
  • Yenny Kandarini ,

Abstract

Background: Age is a factor contributing to atherosclerosis. The elderly was shown to have a higher atherosclerosis incidence. But the studies in the hemodialysis patients were still limited. Objective: Through the examination of carotid intima-media thickness (CIMT), we investigated whether the atherosclerosis was more severe in the elderly than the non-elderly on regular hemodialysis. Methods: A cross-sectional study was conducted at our hemodialysis unit in Sanglah General Hospital from May to June 2016. All regular hemodialysis patients over 18 years old were recruited. But, patients with a malignancy, severe anemia, systemic lupus erythematosus (SLE), an acute infection, a liver function abnormality, a history of long-term steroid therapy, or patients who smoked tobacco were excluded. We examined the CIMT using a grayscale ultrasound. An independent t-test analysis was used to compare the CIMT means of the elderly and the non-elderly patients. Results: Our sample consisted of 30 elderly and 30 non-elderly hemodialysis patients. It was found that the CIMT mean in the elderly was significantly higher than in the non-elderly (0.73±0.1 mm versus 0.58±0.09 mm, p<0.001). Conclusion: More severe atherosclerosis was found in the regular hemodialysis patients in their late life.

References

  1. REFERENCES1. United Nations. World population ageing 2013. New York: United Nations;2013:1-82.2. Dalrymple LS, Mohammed SM, Mu Y, Johansen KL, Chertow GM, Grimes B, etal. Risk of cardiovascular events after infection-related hospitalizations in olderpatients on dialysis. Clin J Am Soc Nephrol. 2011;6:1708-13.3. Coll B, Betriu A, Martinez-Alonso M, Amoedo ML, Arcidiacono MV, Borras M,et al. Large artery calcification on dialysis patients is located in the intima andrelated to atherosclerosis. Clin J Am Soc Nephrol. 2010;6:1-8.4. Cheng S, Bell SM, Zieman SJ. Aging and atherosclerosis. In: Halter JB,Ouslander JG, Tinetti ME, Stephanie S, High KP, Asthana S, eds. Hazzard’sgeriatric medicine and gerontology. 6th ed. New York: McGraw-Hill; 2009:897-908.5. PERNEFRI. Konsensus Dialisis. 1st ed. Jakarta: PERNEFRI; 2003:1-55.6. DeMaeyer E. Preventing and controlling iron deficiency anemia through primaryhealth care. Geneva: WHO; 1989:22-8.7. Wita W. Program intervensi terpadu mengendalikan faktor risiko koroner danmeningkatkan kualitas hidup pasca IMA (dissertation). Surabaya: UniversitasAirlangga; 1992.8. Perhimpunan Reumatologi Indonesia. Diagnosis dan Pengelolaan LupusEritematosus Sistemik. Jakarta: Perhimpunan Reumatologi Indonesia; 2011:1-46.9. Pourafkari M, Bakhtiyari ET, Jalali AH, Shakiba M. Ultrasonic measurement ofcarotid intima–media thickness in a group of Iranian with no cardiovascular riskfactors. Iran J Radiol. 2006;3(3):163-7.10. Patel ML, Radheyshyam CO, Verma A, Sachan R, Kamal R. Impact of carotidintima-media thickness on long-term outcome in hemodialysis patients. N Am JMed Sci. 2015;7(6):281-7.11. Patel ML, Sachan R, Parihar A, Sethi R. Association between intima-mediathickness of the carotid artery and risk factors for cardiovascular disease inpatients on maintenance hemodialysis. Int J Sci Res Publ. 2012;2(4):1-5.12. Paul J, Dasgupta S, Ghosh MK. Carotid artery intima media thickness as asurrogate marker of atherosclerosis in patient with chronic renal failure onhemodialysis. N Am J Med Sci. 2012;4(2):77-80.13. Edo MD, Andres V. Aging, Telomeres, and Atherosclerosis. Cardiovasc Res.2005;66:213-21.14. Robertson CM, Fowkes R, Price JF. Carotid intima-media thickness and theprediction of vascular events. Vasc Med. 2012;17(4):239-48.
  2. Belibou C. Carotid intima-media thickness and plaque as surrogate biomarkers ofatherosclerosis among consecutive women with systemic lupus erythematosus.Rom J Morphol Embryol. 2012;53(1):29-34.16. Gupta V, Lipsitz LA. Orthostatic hypotension in the elderly : diagnosis and treatment. Am J Med. 2007;120:841-7.17. Singh R. Isolated systolic hypertension. Medicine Update. 2012;22:111-6.

How to Cite

Wiradharma, K. G., Kuswardhani, R. A. T., & Kandarini, Y. (2017). Greater carotid intima-media thickness in elderly patients compare to the non-elderly regular hemodialysis patients. Bali Medical Journal, 6(2), 400–404. https://doi.org/10.15562/bmj.v6i2.590

HTML
0

Total
5

Share

Search Panel

Ketut Gede Wiradharma
Google Scholar
Pubmed
BMJ Journal


R. A. Tuty Kuswardhani
Google Scholar
Pubmed
BMJ Journal


Yenny Kandarini
Google Scholar
Pubmed
BMJ Journal