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Radiodermatitis incidents in cancer patients receiving radiotherapy at Haji Adam Malik Central Hospital, Medan-Indonesia

  • Monalisa Manik ,
  • Ariyati Yosi ,
  • Chairiyah Tanjung ,


Abstract

Introduction: Radiodermatitis or radiation dermatitis is a side effect that is produced in the skin and skin adnexal as a consequence of exposure to radiotherapy. There are several factors that influence the occurrence of radiodermatitis: factors related to the patient (intrinsic), such as: age, race, comorbid conditions, nutritional status and factors associated with treatment (extrinsic), such as: dose radiotherapy, fractionation and radiotherapy techniques.

Methods and results : This study is a descriptive observational study with prospective approach in 50 patients who received radiotherapy in Haji Adam Malik Hospital in Medan. History taking by anamneses and dermatological examinations were conducted to all subjects on the first day, 3 weeks and 8 weeks during radiotherapy. From this study, the majority of the patients are women, age 40-60 years old. The most clinical features is erythema macular rash (100%) and the most location is in the coli region. The majority of total dose is 5000-5900 cGy, and the most fractionation used 31-40 fraction.

Conclusion: The results of this study indicate that elderly, high total dose and fractionation leads to an increased risk of radiodermatitis.

Keywords: Radiodermatitis clinical pictures dose radiotherapy

References

  1. Khanna NR, et al. Radiation dermatitis: An overview. Indian J Burns. 2013;21:24-31.
  2. Wells M, MacBride S. Radiation skin reactions. Dalam : Faithfull S, Well M, editor. Supportive care in radiotherapy. New York : Churchill Livingstone. 2003:135-59.
  3. Feight D, Baney T, Bruce S, McQuestion M. Putting evidence into practice: Evidence based interventions for radiation dermatitis.Clinical Journal of Oncology Nursing.201;15(5):481-92.
  4. Brown K, Rzucidlo E. Acute and chronic radiation injury. J. Vasc. Surg. 2011; 53: 155-21.
  5. Isomura M, Oya N, Tachiiri S, et al. IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis. Clin Cancer Res. 2008; 14:6683.
  6. Maryum H, Wahid Z, Ahmad I, Alam M. Frequency of cutaneous manifestations of Radiotherapy. Journal of Pakistan Association of Dermatologists. 2013; 23 (4): 371-7.
  7. Wood G, Casey L, Trotti A. Skin Changes. Dalam : Small W, Woloschak GE, editor. Radiation Toxicity: A Practical Guide. Springer Science. 2006:171-81.
  8. López E,et al.Early and late skin reactions to radiotherapy for breast cancer and their correlation with radiation-induced DNA damage in lymphocytes.Breast Cancer Res.2005; 7:R690.
  9. Mendelsohn FA,et al.Wound care after radiation therapy. Adv Skin Wound Care. 2002;15:216-24.
  10. Edison MN, Johns CM. Acute and Chronic Cutaneous Reactions to Radiotherapy. Dalam : Cognetta AB, Mendenhall WM, editor. Radiation Therapy for Skin Cancer. New York: Springer Science Business Media. 2013:55-69.
  11. Malkinson FD, Panizzon RG. Radiobiology and Radiation effects. Dalam : Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, editor. Fitzpatrick’s Dermatology in General Medicine. Edisi ke-7. New York: McGraw-Hill. 2008: 896-900.
  12. Kelly CG, Peat I. Radiotherapy and Reactions to Ionizing Radiation. Dalam : Burns T, Breathnach S, Cox N, Griffiths C, editor. Rook's Textbook of Dermatology. Edisis 8. Blackwell Publishing 2010:p.79.1-79.18.
  13. Altoparlak U, Koca O, Koca T. Incidence and Risk Factors of the Secondary Skin Infections in Patients with Radiodermatitis. Eurasian J Med. 2011 Dec; 43(3): 177-181.
  14. Barkham AM. Radiotherapy skin reactions and treatments. Prof Nurse. 1993; 8(11):732-6.
  15. Brown K, Rzucidlo E. Acute and chronic radiation injury. J. Vasc. Surg. 2011; 53: 155-21.
  16. Porock D, Kristjanson L, Nikoletti S. Predicting The severity of radiation skin reactions in women with breast cancer. Oncol Nurs Forum.1998; 25: 1019-29.
  17. Tortorelli, G., Di Murro, L., Barbarino, R. et al. Standard or hypofractionated radiotherapy in the postoperative treatment of breast cancer: a retrospective analysis of acute skin toxicity and dose inhomogeneities. BMC Cancer.2013;13:230.
  18. Andrade K, et al. Nursing consultation: evaluation of adherence to self-care in patients undergoing radiotherapy. Rev enferm UERJ, Rio de Janeiro. 2014; 22(5):622-8.
  19. Meyer F, Fortin A, Wang CS et al. Predictors of severe acute and late toxicities in patients with localized head and neck cancer treated with radiation therapy. Int J Radiat Oncol Biol Phys; e-pub ahead of print. 2011.
  20. Langhe et al.: Factors modifying the risk for developing acute skin toxicity after whole-breast intensity modulated radiotherapy. BMC Cancer. 2014 14:711.
  21. Decker RH, Wilson LD. Radiotherapy. Dalam : Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K. Fitzpatrick’s Dermatology in General Medicine. Edisi ke-8. New York: Mc Graw-Hill. 2012;p.2890-2899.

How to Cite

Manik, M., Yosi, A., & Tanjung, C. (2018). Radiodermatitis incidents in cancer patients receiving radiotherapy at Haji Adam Malik Central Hospital, Medan-Indonesia. Bali Medical Journal, 7(2). https://doi.org/10.15562/bmj.v7i2.776
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Monalisa Manik
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Ariyati Yosi
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Chairiyah Tanjung
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