Skip to main content Skip to main navigation menu Skip to site footer

Restoration of erythrocyte microrheological peculiarities in 5-6-year-old children with scoliosis after daily usage of medioprophylactic clothes for six months



Efficient correction methods should be applied early at the detection of scoliosis. One of them is medioprophylactic clothes. However, the effect of medioprophylactic clothes towards the dynamics of erythrocyte microrheological features in children with scoliosis has not been fully studied.


In this study, we tracked indices changes of erythrocyte cytoarchitecture and aggregation in thirty-nine 5-6-year-old children with grade I-II scoliosis who wore medioprophylactic clothes (designed by one of the authors) daily for 6 months. Thirty-four healthy subjects were enrolled for the control group. The measurement was conducted at the beginning of the research and after 3 and 6 months of intervention.


At their initial state of the observation, the experimental group had worse erythrocyte microrheological features because of physical development inhibition. Daily usage of medioprophylactic clothes for six months reduced the evidence of spinal curvature, increased force, and tolerance of body muscles, lowered reversible and irreversible modified erythrocyte, and weakened spontaneous erythrocyte aggregation.


  1. Topalis C., Anna Grauers , Diarbakerli E., Danielsson A., Gerdhem P. Neck and back problems in adults with idiopathic scoliosis diagnosed in youth: an observational study of prevalence, change over a mean four year time period and comparison with a control group. Scoliosis and Spinal Disorders. 2017; 8:12-20. doi: 10.1186/s13013-017-0125-z
  2. Chirjatjeva Т.V., Tsibulskaya Ð.S., Stogniy О.M., Kojnosov, Ð.P. Peculiarities of physical development bof persons with spinal deformities. Medical Science and Education of the Urals. 2013; 14 (1): 88-92.
  3. Коvalenkо V.S., Dzhandarovа Т.I. Мineral metabolism and indices of cardio-vascular system in children with inborn scoliosis and clubfoot. Bulletin of Medical Internet-Conferences. 2011; 1(7): 86-88.
  4. Chernozemov V.G., Ðbramovа Ðœ.Ð. Functional abilities of the system of external respiration at scoliotic disease in schoolchildren. Fundamental investigations. 2012; 2-1:159-162.
  5. Nagibina E.V. Features of microrheological properties of erythrocytes in children of primary school age with a different functional state of the musculoskeletal system: the dissertation ... candidate of biological sciences. Kursk, 2013;177.
  6. Lapshina E.V. The condition of musculoskeletal function and activity of platelets in children with scoliosis: the dissertation ... candidate of biological sciences. Kursk, 2011;152.
  7. Sukhinin М.V. Results of prophylactic examinations of children in conditions of Moscow City polyclinic. Advances of Modern Pediatrics. 2014;13(1): 6-8.
  8. Skoryatina I.A., Zavalishina S.Yu. Ability to aggregation of basic regular blood elements of patients with hypertension anddyslipidemia receiving non-medication andsimvastatin. Bali Medical Journal. 2017; 6(3):514-520. doi:10.15562/bmj.v6i3.552
  9. Kotova O.V., Zavalishina S.Yu., Makurina O.N., Kiperman Ya.V., Savchenko A.P., Skoblikova T.V., Skripleva E.V., Zacepin V.I., Skriplev A.V., Andreeva V.Yu. Impact estimation of long regular exercise on hemostasis and blood rheological features of patients with incipient hypertension. Bali Medical Journal. 2017; 6(3):514-520. doi:10.15562/bmj.v6i3.552
  10. Zavalishina S.Yu., Vatnikov Yu.A., Kulikov E.V., Yagnikov S.A., Karamyan A.S., Sturov N.V., Byakhova V.M., Kochneva M.V., Petryaeva A.V. Diagnostics of erythrocytes’ microrheological features and early abnormalities of rats in the model of experimental hypertension development. Bali Medical Journal. 2017; 6(3): 470-475. doi:10.15562/bmj.v6i3.589
  11. Vatnikov Yu.A., Zavalishina S.Yu., Kulikov E.V., Vilkovysky I.F., Nikishov A.A., Drukovsky S.G., Krotova E.A., Khomenets N.G., Bolshakova M.V. Correctional abilities of regular muscle activity in relation to erythrocytes’ microrheological features of rats with experimentally developed hypertension. Bali Medical Journal. 2017; 6(3):449-456. doi:10.15562/bmj.v6i3.586
  12. Zavalishina S.Y., Nagibina E.V. Dynamics of microrheology characteristics of erythrocyte in children 7-8 years with scoliosis with therapeutic physical training and massage. Technologies of Living Systems. 2012; 9(4):29-34.
  13. Yavorskiy Ð.B., Кoss V.V., Sologubov Е.G., Zorja N.Ð. Examination results of schoolchildren with bearing deformity and scoliosis with the help of 3D-scannerometry of spinal column. Advances of Practical Pediatrics. 2009;4(3):73-76.
  14. Andreeva E.G., Mokeyeva N.S., Glushkova T.V., Kharlova O. N., Chulkova E.N. Rehabilitation and prevention of disability: clothes and corrective devices: Handbook. Moscow: MSUDT; 2010:90.
  15. Bikbulatova A.A., Andreeva E.G. Method of determining requirements for therapeutic and preventive garments. Sewing industry. 2013;1:37-40.
  16. Bikbulatova A.A., Borisevich S.S., Andreeva E.G. Development of the composite material for the production of therapeutic-preventive school clothes. Design. Materials. Technology. 2016;4(44):53-56.
  17. Коlchin D.V. Early diagnostics of dysplastic and inborn scoliosis. Genius of Orthopedics. 2012;1: 54-59.
  18. Sytko L.Ð., Zlobin S.B., Popov Е.G., Larkin I.I., Zlobin, B.B. Diagnostics of progressing scoliosis in children and teenagers. Chronicles of the United Fund of Electronic Resources. Science and Education. 2016; 4(83):63.
  19. Gavrilov V.B., Mishkorudnaya M.I. Spectrophotometric determination of the content of lipid hydroperoxides in blood plasma. Laboratory work. 1983; 3:33-36.
  20. Volchegorskij I.A., Dolgushin I.I., Kolesnikov O.L., Cejlikman V.Je. Experimental modeling and laboratory assessment of adaptive reactions of the organism. Cheljabinsk, 2000:167.
  21. Metel'skaja V.A., Gumanova N.G. Nitric oxide: a role in the regulation of biological functions, methods for the determination of human blood. Laboratornaja medicina 2005 ; 7 : 19-24.
  22. Kolb V.G., Kamyshnikov V.S. Handbook of Clinical Chemistry. Minsk: "Belarus", 1982:367.
  23. Kozinets G.I., Makarov V. A. Study of the blood system in clinical practice. Moscow, 1998. 480.
  24. Kayumova R.F., Bikbulatova A.A. The outerwear correcting a bearing. Patent for the invention RU 2211651, 16.11.2001.
  25. Vatnikov Yu.A., Zavalishina S.Yu., Pliushchikov V.G., Kuznetsov V.I., Seleznev S.B., Kubatbekov T.S., Rystsova E.O., Parshina V.I. Early-changes diagnostics of erythrocytes microrheological features in the model of dyslipidemia development in rats at the late stages of ontogenesis. Bali Medical Journal. 2017;6(1): 216-222. doi: 10.15562/bmj.v6i1.483
  26. Zavalishina S.Yu. Hemostatic activity of a vascular wall at newborn calfs. Russian Agricultural Sciences. 2012; 1:37-39
  27. Zavalishina S.Yu. Vascular hemostasis at calves in milk-and-vegetable phase of feeding. Zootekhniya. 2012;2:21.
  28. Zavalishina S.Yu. Activity of a vascular hemostasis at calfs of a dairy food. Russian Agricultural Sciences. 2012;4:49-51.

How to Cite

Bikbulatova, A., Andreeva, E., & Medvedev, I. (2018). Restoration of erythrocyte microrheological peculiarities in 5-6-year-old children with scoliosis after daily usage of medioprophylactic clothes for six months. Bali Medical Journal, 7(2).




Search Panel